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On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO
A new mechanism for formation of 7-ketocholesterol was recently described involving cytochrome P-450 (CYP)7A1-catalyzed conversion of 7-dehydrocholesterol into 7-ketocholesterol with cholesterol-7,8-epoxide as a side product. Some patients with cerebrotendinous xanthomatosis (CTX) and all patients w...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Biochemistry and Molecular Biology
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031947/ https://ncbi.nlm.nih.gov/pubmed/24771866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P048603 |
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