RNA binding protein HuR regulates the expression of ABCA1

ABCA1 is a major regulator of cellular cholesterol efflux and plasma HDL biogenesis. Even though the transcriptional activation of ABCA1 is well established, the posttranscriptional regulation of ABCA1 expression is poorly understood. Here, we investigate the potential contribution of the RNA bindin...

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Detalhes bibliográficos
Main Authors: Ramírez, Cristina M., Lin, Chin Sheng, Abdelmohsen, Kotb, Goedeke, Leigh, Yoon, Je-Hyun, Madrigal-Matute, Julio, Martin-Ventura, Jose L., Vo, Dat T., Uren, Philip J., Penalva, Luiz O., Gorospe, Myriam, Fernández-Hernando, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031938/
https://ncbi.nlm.nih.gov/pubmed/24729624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M044925
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