Botch is a γ-glutamyl Cyclotransferase that Deglycinates and Antagonizes Notch

Botch promotes embryonic neurogenesis through inhibition of Notch-1 signaling through inhibition of the initial S1 furin-like cleavage step of Notch maturation. The biochemical process by which Botch inhibits Notch maturation is not known. Here we show that Botch has γ-glutamyl cyclotransferase (GGC...

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Detalhes bibliográficos
Main Authors: Chi, Zhikai, Byrne, Sean T., Dolinko, Andrew, Harraz, Maged M., Kim, Min-Sik, Umanah, George, Zhong, Jun, Chen, Rong, Zhang, Jianmin, Xu, Jinchong, Chen, Li, Pandey, Akhilesh, Dawson, Ted M., Dawson, Valina L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031649/
https://ncbi.nlm.nih.gov/pubmed/24767995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.048
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