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Botch is a γ-glutamyl Cyclotransferase that Deglycinates and Antagonizes Notch
Botch promotes embryonic neurogenesis through inhibition of Notch-1 signaling through inhibition of the initial S1 furin-like cleavage step of Notch maturation. The biochemical process by which Botch inhibits Notch maturation is not known. Here we show that Botch has γ-glutamyl cyclotransferase (GGC...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031649/ https://ncbi.nlm.nih.gov/pubmed/24767995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.048 |
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