Botch (NPG7) Promotes Neurogenesis by Antagonizing Notch

Regulation of self-renewal and differentiation of neural stem cells is still poorly understood. Here we investigate the role of a developmentally expressed protein, Botch, which blocks Notch, in neocortical development. Downregulation of Botch in vivo leads to cellular retention in the ventricular a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Chi, Zhikai, Zhang, Jianmin, Tokunaga, Akinori, Harraz, Maged M., Byrne, Sean T., Dolinko, Andrew, Xu, Jing, Blackshaw, Seth, Gaiano, Nicholas, Dawson, Ted M., Dawson, Valina L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331935/
https://ncbi.nlm.nih.gov/pubmed/22445366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.02.011
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker