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Botch (NPG7) Promotes Neurogenesis by Antagonizing Notch
Regulation of self-renewal and differentiation of neural stem cells is still poorly understood. Here we investigate the role of a developmentally expressed protein, Botch, which blocks Notch, in neocortical development. Downregulation of Botch in vivo leads to cellular retention in the ventricular a...
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3331935/ https://ncbi.nlm.nih.gov/pubmed/22445366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.02.011 |
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