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Composite RNAi-Microsponges Form through Self-Assembly of the Organic and Inorganic Products of Transcription

Inorganic nanostructures have been used extensively to package nucleic acids into forms useful for therapeutic applications. Here we report that the two products of transcription, RNA and inorganic pyrophosphate, can self-assemble to form composite microsponge structures composed of nanocrystalline...

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Autors principals: Shopsowitz, Kevin E., Roh, Young Hoon, Deng, Zhou J., Morton, Stephen W., Hammond, Paula T.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031615/
https://ncbi.nlm.nih.gov/pubmed/24851252
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