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Adducin Is Required for Desmosomal Cohesion in Keratinocytes
Adducin is a protein organizing the cortical actin cytoskeleton and a target of RhoA and PKC signaling. However, the role for intercellular cohesion is unknown. We found that adducin silencing induced disruption of the actin cytoskeleton, reduced intercellular adhesion of human keratinocytes, and de...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031542/ https://ncbi.nlm.nih.gov/pubmed/24711455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527127 |
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