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Adducin Is Required for Desmosomal Cohesion in Keratinocytes

Adducin is a protein organizing the cortical actin cytoskeleton and a target of RhoA and PKC signaling. However, the role for intercellular cohesion is unknown. We found that adducin silencing induced disruption of the actin cytoskeleton, reduced intercellular adhesion of human keratinocytes, and de...

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Detalhes bibliográficos
Main Authors: Rötzer, Vera, Breit, Andreas, Waschke, Jens, Spindler, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031542/
https://ncbi.nlm.nih.gov/pubmed/24711455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527127
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