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Adducin Is Required for Desmosomal Cohesion in Keratinocytes

Adducin is a protein organizing the cortical actin cytoskeleton and a target of RhoA and PKC signaling. However, the role for intercellular cohesion is unknown. We found that adducin silencing induced disruption of the actin cytoskeleton, reduced intercellular adhesion of human keratinocytes, and de...

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Bibliografische gegevens
Hoofdauteurs: Rötzer, Vera, Breit, Andreas, Waschke, Jens, Spindler, Volker
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031542/
https://ncbi.nlm.nih.gov/pubmed/24711455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527127
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