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Ceramide mediates lung fibrosis in cystic fibrosis

Fibrosis of the lung is one of the major clinical problems of cystic fibrosis and chronic obstructive pulmonary disease. However, the molecular mechanisms leading to pulmonary fibrosis are poorly characterized and require definition. Here, we demonstrate that chronic accumulation of ceramide in the...

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Detalhes bibliográficos
Main Authors: Ziobro, Regan, Henry, Brian, Edwards, Michael J., Lentsch, Alex B., Gulbins, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031452/
https://ncbi.nlm.nih.gov/pubmed/23523785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.03.032
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