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Ceramide mediates lung fibrosis in cystic fibrosis

Fibrosis of the lung is one of the major clinical problems of cystic fibrosis and chronic obstructive pulmonary disease. However, the molecular mechanisms leading to pulmonary fibrosis are poorly characterized and require definition. Here, we demonstrate that chronic accumulation of ceramide in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ziobro, Regan, Henry, Brian, Edwards, Michael J., Lentsch, Alex B., Gulbins, Erich
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031452/
https://ncbi.nlm.nih.gov/pubmed/23523785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.03.032
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