Pre-Clinical Characterization of Dacomitinib (PF-00299804), an Irreversible Pan-ErbB Inhibitor, Combined with Ionizing Radiation for Head and Neck Squamous Cell Carcinoma

Epidermal growth factor receptor (EGFR) is over-expressed in nearly all cases of squamous cell carcinoma of the head and neck (SCCHN), and is an important driver of disease progression. EGFR targeted therapies have demonstrated clinical benefit for SCCHN treatment. In this report, we investigated th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Williams, Justin P., Kim, Inki, Ito, Emma, Shi, Wei, Yue, Shijun, Siu, Lillian L., Waldron, John, O'Sullivan, Brian, Yip, Kenneth W., Liu, Fei-Fei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031184/
https://ncbi.nlm.nih.gov/pubmed/24853121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098557
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