Dacomitinib, a pan-inhibitor of ErbB receptors, suppresses growth and invasive capacity of chemoresistant ovarian carcinoma cells

Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy worldwide. Development of chemoresistance and peritoneal dissemination of EOC cells are the major reasons for low survival rate. Targeting signal transduction pathways which promote therapy resistance and metastatic dissemi...

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Publicado no:Sci Rep
Main Authors: Momeny, Majid, Zarrinrad, Ghazaleh, Moghaddaskho, Farima, Poursheikhani, Arash, Sankanian, Ghazaleh, Zaghal, Azam, Mirshahvaladi, Shahab, Esmaeili, Fatemeh, Eyvani, Haniyeh, Barghi, Farinaz, Sabourinejad, Zahra, Alishahi, Zivar, Yousefi, Hassan, Ghasemi, Reza, Dardaei, Leila, Bashash, Davood, Chahardouli, Bahram, Dehpour, Ahmad R., Tavakkoly-Bazzaz, Javad, Alimoghaddam, Kamran, Ghavamzadeh, Ardeshir, Ghaffari, Seyed H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482808/
https://ncbi.nlm.nih.gov/pubmed/28646172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04147-0
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