Dacomitinib, a pan-inhibitor of ErbB receptors, suppresses growth and invasive capacity of chemoresistant ovarian carcinoma cells

Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy worldwide. Development of chemoresistance and peritoneal dissemination of EOC cells are the major reasons for low survival rate. Targeting signal transduction pathways which promote therapy resistance and metastatic dissemi...

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Publicat a:Sci Rep
Autors principals: Momeny, Majid, Zarrinrad, Ghazaleh, Moghaddaskho, Farima, Poursheikhani, Arash, Sankanian, Ghazaleh, Zaghal, Azam, Mirshahvaladi, Shahab, Esmaeili, Fatemeh, Eyvani, Haniyeh, Barghi, Farinaz, Sabourinejad, Zahra, Alishahi, Zivar, Yousefi, Hassan, Ghasemi, Reza, Dardaei, Leila, Bashash, Davood, Chahardouli, Bahram, Dehpour, Ahmad R., Tavakkoly-Bazzaz, Javad, Alimoghaddam, Kamran, Ghavamzadeh, Ardeshir, Ghaffari, Seyed H.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482808/
https://ncbi.nlm.nih.gov/pubmed/28646172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04147-0
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