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Assessment of Blood-Brain Barrier Function and the Neuroinflammatory Response in the Rat Brain by Using Cerebral Open Flow Microperfusion (cOFM)

Blood-brain barrier (BBB) impairment in systemic inflammation leads to neuroinflammation. Several factors including cytokines, chemokines and signal transduction molecules are implicated in BBB dysfunction in response to systemic inflammation. Here, we have adopted a novel in vivo technique; namely,...

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Detalhes bibliográficos
Main Authors: Ghosh, Arijit, Birngruber, Thomas, Sattler, Wolfgang, Kroath, Thomas, Ratzer, Maria, Sinner, Frank, Pieber, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031165/
https://ncbi.nlm.nih.gov/pubmed/24852285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098143
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