Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence

BACKGROUND: The availability of generic topical dermatological drug products is constrained by the limited methods established to assess topical bioequivalence (BE). A novel cutaneous pharmacokinetic approach, dermal open-flow microperfusion (dOFM), can continuously assess the rate and extent to whi...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Bodenlenz, Manfred, Tiffner, Katrin I., Raml, Reingard, Augustin, Thomas, Dragatin, Christian, Birngruber, Thomas, Schimek, Denise, Schwagerle, Gerd, Pieber, Thomas R., Raney, Sam G., Kanfer, Isadore, Sinner, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222896/
https://ncbi.nlm.nih.gov/pubmed/27539717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0442-z
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