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The Role of Non-Native Interactions in the Folding of Knotted Proteins: Insights from Molecular Dynamics Simulations

For several decades, the presence of knots in naturally-occurring proteins was largely ruled out a priori for its supposed incompatibility with the efficiency and robustness of folding processes. For this very same reason, the later discovery of several unrelated families of knotted proteins motivat...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Covino, Roberto, Škrbić, Tatjana, Beccara, Silvio a, Faccioli, Pietro, Micheletti, Cristian
التنسيق: Artigo
اللغة:Inglês
منشور في: MDPI 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030985/
https://ncbi.nlm.nih.gov/pubmed/24970203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom4010001
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