A variational Bayes discrete mixture test for rare variant association

Recently, many statistical methods have been proposed to test for associations between rare genetic variants and complex traits. Most of these methods test for association by aggregating genetic variations within a predefined region, such as a gene. Although there is evidence that “aggregate” tests...

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Detalhes bibliográficos
Main Authors: Logsdon, Benjamin A., Dai, James Y., Auer, Paul L., Johnsen, Jill M., Ganesh, Santhi K., Smith, Nicholas L., Wilson, James G., Tracy, Russell P., Lange, Leslie A., Jiao, Shuo, Rich, Stephen S., Lettre, Guillaume, Carlson, Christopher S., Jackson, Rebecca D., O’Donnell, Christopher J., Wurfel, Mark M., Nickerson, Deborah A., Tang, Hua, Reiner, Alexander P., Kooperberg, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030763/
https://ncbi.nlm.nih.gov/pubmed/24482836
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