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Imputation of Exome Sequence Variants into Population- Based Samples and Blood-Cell-Trait-Associated Loci in African Americans: NHLBI GO Exome Sequencing Project

Researchers have successfully applied exome sequencing to discover causal variants in selected individuals with familial, highly penetrant disorders. We demonstrate the utility of exome sequencing followed by imputation for discovering low-frequency variants associated with complex quantitative trai...

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Bibliografische gegevens
Hoofdauteurs: Auer, Paul L., Johnsen, Jill M., Johnson, Andrew D., Logsdon, Benjamin A., Lange, Leslie A., Nalls, Michael A., Zhang, Guosheng, Franceschini, Nora, Fox, Keolu, Lange, Ethan M., Rich, Stephen S., O’Donnell, Christopher J., Jackson, Rebecca D., Wallace, Robert B., Chen, Zhao, Graubert, Timothy A., Wilson, James G., Tang, Hua, Lettre, Guillaume, Reiner, Alex P., Ganesh, Santhi K., Li, Yun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487117/
https://ncbi.nlm.nih.gov/pubmed/23103231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.08.031
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