Modulation of de novo purine biosynthesis leads to activation of AMPK and results in improved glucose handling and insulin sensitivity

BACKGROUND: AMP activated protein kinase (AMPK) regulates key metabolic reactions and plays a major role in glucose homeostasis. Activating the AMPK is considered as one of the potential therapeutic strategies in treating type-2 diabetes. However, targeting AMPK by small molecule mediated approach c...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sadasivan, Satish Kumar, Vasamsetti, Balamuralikrishna, Singh, Jaideep, Siddaraju, Nethra, Khan, Khaiser Mehdi, Oommen, Anup Mammen, Jagannath, Madanalli R, Rao, Raghavendra Pralhada
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030739/
https://ncbi.nlm.nih.gov/pubmed/24855629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2251-6581-13-51
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires