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Erlotinib for Progressive Vestibular Schwannoma in Neurofibromatosis 2 Patients

In vitro treatment of Nf2-deficient cells with epidermal growth factor receptor (EGFR) inhibitors can inhibit cellular proliferation. We retrospectively assessed the effect of erlotinib (150 mg daily) on eleven consecutive NF2 patients with progressive VS who were poor candidates for standard therap...

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Hlavní autoři: Plotkin, Scott R., Halpin, Chris, McKenna, Michael J., Loeffler, Jay S., Batchelor, Tracy T., Barker, Fred G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030413/
https://ncbi.nlm.nih.gov/pubmed/20736812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0b013e3181eb328a
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