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Erlotinib for Progressive Vestibular Schwannoma in Neurofibromatosis 2 Patients

In vitro treatment of Nf2-deficient cells with epidermal growth factor receptor (EGFR) inhibitors can inhibit cellular proliferation. We retrospectively assessed the effect of erlotinib (150 mg daily) on eleven consecutive NF2 patients with progressive VS who were poor candidates for standard therap...

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Autors principals: Plotkin, Scott R., Halpin, Chris, McKenna, Michael J., Loeffler, Jay S., Batchelor, Tracy T., Barker, Fred G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030413/
https://ncbi.nlm.nih.gov/pubmed/20736812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0b013e3181eb328a
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