Suggested response criteria for phase II antitumor drug studies for neurofibromatosis type 2 related vestibular schwannoma

Neurofibromatosis type 2 (NF2) is a tumor suppressor gene syndrome characterized by multiple schwannomas, especially vestibular schwannomas (VS), and meningiomas. Anticancer drug trials are now being explored, but there are no standardized endpoints in NF2. We review the challenges of NF2 clinical t...

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Autori principali: Plotkin, Scott R., Halpin, Chris, Blakeley, Jaishri O., Slattery, William H., Welling, D. Bradley, Chang, Susan M., Loeffler, Jay S., Harris, Gordon J., Sorensen, A. Gregory, McKenna, Michael J., Barker, Fred G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036446/
https://ncbi.nlm.nih.gov/pubmed/19430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-009-9867-7
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