Suggested response criteria for phase II antitumor drug studies for neurofibromatosis type 2 related vestibular schwannoma

Neurofibromatosis type 2 (NF2) is a tumor suppressor gene syndrome characterized by multiple schwannomas, especially vestibular schwannomas (VS), and meningiomas. Anticancer drug trials are now being explored, but there are no standardized endpoints in NF2. We review the challenges of NF2 clinical t...

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Hlavní autoři: Plotkin, Scott R., Halpin, Chris, Blakeley, Jaishri O., Slattery, William H., Welling, D. Bradley, Chang, Susan M., Loeffler, Jay S., Harris, Gordon J., Sorensen, A. Gregory, McKenna, Michael J., Barker, Fred G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036446/
https://ncbi.nlm.nih.gov/pubmed/19430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-009-9867-7
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