Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors.

The gene transfer efficiency of human hematopoietic stem cells is still inadequate for efficient gene therapy of most disorders. To overcome this problem, a selectable retroviral vector system for gene therapy has been developed for gene therapy of Gaucher disease. We constructed a bicistronic retro...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Migita, M, Medin, J A, Pawliuk, R, Jacobson, S, Nagle, J W, Anderson, S, Amiri, M, Humphries, R K, Karlsson, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12075
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