Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors.

The gene transfer efficiency of human hematopoietic stem cells is still inadequate for efficient gene therapy of most disorders. To overcome this problem, a selectable retroviral vector system for gene therapy has been developed for gene therapy of Gaucher disease. We constructed a bicistronic retro...

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Detaylı Bibliyografya
Yayımlandı:	Proc Natl Acad Sci U S A
Asıl Yazarlar:	Migita, M, Medin, J A, Pawliuk, R, Jacobson, S, Nagle, J W, Anderson, S, Amiri, M, Humphries, R K, Karlsson, S
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	National Academy of Sciences 1995
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12075
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Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors.

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