Transiently Produced Hypochlorite Is Responsible for the Irreversible Inhibition of Chlorite Dismutase

[Image: see text] Chlorite dismutases (Clds) are heme b-containing prokaryotic oxidoreductases that catalyze the reduction of chlorite to chloride with the concomitant release of molecular oxygen. Over time, they are irreversibly inactivated. To elucidate the mechanism of inactivation and investigat...

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Hlavní autoři: Hofbauer, Stefan, Gruber, Clemens, Pirker, Katharina F., Sündermann, Axel, Schaffner, Irene, Jakopitsch, Christa, Oostenbrink, Chris, Furtmüller, Paul G., Obinger, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029776/
https://ncbi.nlm.nih.gov/pubmed/24754261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500401k
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