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Mechanism of reaction of chlorite with mammalian heme peroxidases

This study demonstrates that heme peroxidases from different superfamilies react differently with chlorite. In contrast to plant peroxidases, like horseradish peroxidase (HRP), the mammalian counterparts myeloperoxidase (MPO) and lactoperoxidase (LPO) are rapidly and irreversibly inactivated by chlo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jakopitsch, Christa, Pirker, Katharina F., Flemmig, Jörg, Hofbauer, Stefan, Schlorke, Denise, Furtmüller, Paul G., Arnhold, Jürgen, Obinger, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003552/
https://ncbi.nlm.nih.gov/pubmed/24632343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2014.02.010
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