Transiently Produced Hypochlorite Is Responsible for the Irreversible Inhibition of Chlorite Dismutase

[Image: see text] Chlorite dismutases (Clds) are heme b-containing prokaryotic oxidoreductases that catalyze the reduction of chlorite to chloride with the concomitant release of molecular oxygen. Over time, they are irreversibly inactivated. To elucidate the mechanism of inactivation and investigat...

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Detalhes bibliográficos
Main Authors: Hofbauer, Stefan, Gruber, Clemens, Pirker, Katharina F., Sündermann, Axel, Schaffner, Irene, Jakopitsch, Christa, Oostenbrink, Chris, Furtmüller, Paul G., Obinger, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029776/
https://ncbi.nlm.nih.gov/pubmed/24754261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500401k
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