Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas

BACKGROUND: Corticotropin-releasing factor type 2 receptors (CRFR2) are suggested to facilitate successful recovery from stress to maintain mental health. They are abundant in the midbrain raphe nuclei, where they regulate serotonergic neuronal activity and have been demonstrated to mediate behaviou...

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Bibliografiske detaljer
Main Authors: Issler, Orna, Carter, Roderick N, Paul, Evan D, Kelly, Paul AT, Olverman, Henry J, Neufeld-Cohen, Adi, Kuperman, Yael, Lowry, Christopher A, Seckl, Jonathan R, Chen, Alon, Jamieson, Pauline M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029322/
https://ncbi.nlm.nih.gov/pubmed/24447313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-5380-4-1
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