Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge

BACKGROUND: The corticotropin-releasing factor type 2 receptor (CRFR2) is suggested to play an important role in aiding recovery from acute stress, but any chronic effects of CRFR2 activation are unknown. CRFR2 in the midbrain raphé nuclei modulate serotonergic activity of this key source of seroton...

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Detalhes bibliográficos
Main Authors: Neufeld-Cohen, Adi, Kelly, Paul A.T., Paul, Evan D., Carter, Roderick N., Skinner, Elizabeth, Olverman, Henry J., Vaughan, Joan M., Issler, Orna, Kuperman, Yael, Lowry, Christopher A., Vale, Wylie W., Seckl, Jonathan R., Chen, Alon, Jamieson, Pauline M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Priority Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430862/
https://ncbi.nlm.nih.gov/pubmed/22704666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.05.005
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