Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas

BACKGROUND: Corticotropin-releasing factor type 2 receptors (CRFR2) are suggested to facilitate successful recovery from stress to maintain mental health. They are abundant in the midbrain raphe nuclei, where they regulate serotonergic neuronal activity and have been demonstrated to mediate behaviou...

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Detalhes bibliográficos
Main Authors: Issler, Orna, Carter, Roderick N, Paul, Evan D, Kelly, Paul AT, Olverman, Henry J, Neufeld-Cohen, Adi, Kuperman, Yael, Lowry, Christopher A, Seckl, Jonathan R, Chen, Alon, Jamieson, Pauline M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029322/
https://ncbi.nlm.nih.gov/pubmed/24447313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-5380-4-1
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