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SNPs in microRNA Binding Sites as Prognostic and Predictive Cancer Biomarkers

Single nucleotide polymorphisms within microRNA (miRNA) binding sites comprise a novel genre of cancer biomarkers. Since miRNA regulation is dependent on sequence complementarity between the mRNA transcript and the miRNA, even single nucleotide aberrations can have significant effects. Over the past...

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Bibliographic Details
Main Authors: Preskill, Carina, Weidhaas, Joanne B.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028830/
https://ncbi.nlm.nih.gov/pubmed/23614619
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