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SNPing cancer in the bud: microRNA and microRNA-target site polymorphisms as diagnostic and prognostic biomarkers in cancer

MicroRNAs are master regulators of gene expression and control many biological pathways such as cell growth, differentiation and apoptosis. Deregulation of microRNA expression and activity results in a myriad of diseases including cancer. Recently, several reports have indicated that single nucleoti...

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Detalhes bibliográficos
Main Authors: Salzman, David W., Weidhaas, Joanne B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546232/
https://ncbi.nlm.nih.gov/pubmed/22964086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.08.016
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