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SNPs in microRNA Binding Sites as Prognostic and Predictive Cancer Biomarkers

Single nucleotide polymorphisms within microRNA (miRNA) binding sites comprise a novel genre of cancer biomarkers. Since miRNA regulation is dependent on sequence complementarity between the mRNA transcript and the miRNA, even single nucleotide aberrations can have significant effects. Over the past...

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Detalhes bibliográficos
Main Authors: Preskill, Carina, Weidhaas, Joanne B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028830/
https://ncbi.nlm.nih.gov/pubmed/23614619
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