Viral Genetic Determinants of H5N1 Influenza Viruses That Contribute to Cytokine Dysregulation

Human disease caused by highly pathogenic avian influenza (H5N1) is associated with fulminant viral pneumonia and mortality rates in excess of 60%. Cytokine dysregulation is thought to contribute to its pathogenesis. In comparison with human seasonal influenza (H1N1) viruses, clade 1, 2.1, and 2.2 H...

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Detalhes bibliográficos
Main Authors: Mok, Ka Pun, Wong, Charmaine H. K., Cheung, Chung Y., Chan, Michael C., Lee, Suki M. Y., Nicholls, John M., Guan, Yi, Peiris, Joseph S. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028720/
https://ncbi.nlm.nih.gov/pubmed/19694514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/605606
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