Proinflammatory Cytokine Response and Viral Replication in Mouse Bone Marrow Derived Macrophages Infected with Influenza H1N1 and H5N1 Viruses

The pathogenesis of human influenza H5N1 virus infection remains poorly understood and controversial. Cytokine dysregulation in human infection has been hypothesized to contribute to disease severity. We developed in vitro cultures of mouse bone marrow derived macrophages (BMDMΦ) from C57BL/6N mouse...

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Main Authors: Chan, Renee W. Y., Leung, Connie Y. H., Nicholls, John M., Peiris, J. S. Malik, Chan, Michael C. W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511392/
https://ncbi.nlm.nih.gov/pubmed/23226456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051057
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