Macrophages promote polycystic kidney disease progression

Renal M2-like macrophages have critical roles in tissue repair stimulating tubule cell proliferation and, if they remain, fibrosis. M2-like macrophages have also been implicated in promoting cyst expansion in mouse models of autosomal dominant polycystic kidney disease (ADPKD). While renal macrophag...

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Hauptverfasser: Swenson-Fields, Katherine I., Vivian, Carolyn J., Salah, Sally M., Peda, Jacqueline D., Davis, Bradley M., van Rooijen, Nico, Wallace, Darren P., Fields, Timothy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028685/
https://ncbi.nlm.nih.gov/pubmed/23423256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.446
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