Evaluation of Tris[2-(Acryloyloxy)Ethyl]Isocyanurate Cross-Linked Polyethylenimine as Antisense Morpholino Oligomer Delivery Vehicle in Cell Culture and Dystrophic mdx Mice

Hyperbranched poly(ester amine)s (PEAs) based on tris[2-(acryloyloxy)ethyl]isocyanurate (TAEI) cross-linked low-molecular-weight polyethylenimine (Mw: 0.8k/1.2k/2.0k) have been evaluated for delivering antisense phosphorodiamidate morpholino oligomer (PMO) in vitro and in vivo in the dystrophic mdx...

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Autors principals: Wang, Mingxing, Wu, Bo, Tucker, Jay D., Lu, Peijuan, Cloer, Caryn, Lu, Qi Long
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028087/
https://ncbi.nlm.nih.gov/pubmed/24405395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.156
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