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Intraarterial Mitoxantrone Delivery in Rabbits: An Optical Pharmacokinetic Study
BACKGROUND: Several human studies have demonstrated the feasibility of intraarterial delivery of mitoxantrone in systemic malignancies. Computational models predict that intraarterial bolus injection of mitoxatrone during transient cerebral hypoperfusion will enhance brain tissue drug deposition com...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4028021/ https://ncbi.nlm.nih.gov/pubmed/21430588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/NEU.0b013e3182181b67 |
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