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Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation

In order to identify genes involved in renal carcinogenesis, we analyzed the expression profile of renal cell carcinomas (RCCs) using microarrays consisting of 27,648 cDNA or ESTs, and found a small heat shock protein, HSPB7, to be significantly and commonly downregulated in RCC. Subsequent quantita...

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Bibliografische gegevens
Hoofdauteurs: LIN, JIAYING, DENG, ZHENZHONG, TANIKAWA, CHIZU, SHUIN, TARO, MIKI, TSUNEHARU, MATSUDA, KOICHI, NAKAMURA, YUSUKE
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027944/
https://ncbi.nlm.nih.gov/pubmed/24585183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2314
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