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Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation

In order to identify genes involved in renal carcinogenesis, we analyzed the expression profile of renal cell carcinomas (RCCs) using microarrays consisting of 27,648 cDNA or ESTs, and found a small heat shock protein, HSPB7, to be significantly and commonly downregulated in RCC. Subsequent quantita...

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Autores principales: LIN, JIAYING, DENG, ZHENZHONG, TANIKAWA, CHIZU, SHUIN, TARO, MIKI, TSUNEHARU, MATSUDA, KOICHI, NAKAMURA, YUSUKE
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027944/
https://ncbi.nlm.nih.gov/pubmed/24585183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2314
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