Design and Syntheses of Anti-Tuberculosis Agents Inspired by BTZ043 Using a Scaffold Simplification Strategy

[Image: see text] Tuberculosis (TB), a disease caused by Mycobacterium tuberculosis (Mtb), is a global public health concern because of the emergence of various resistant strains. Benzothiazin-4-ones (BTZs), represented by BTZ043, are a promising new class of agents for the treatment of tuberculosis...

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Hauptverfasser: Tiwari, Rohit, Möllmann, Ute, Cho, Sanghyun, Franzblau, Scott G., Miller, Patricia A., Miller, Marvin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027775/
https://ncbi.nlm.nih.gov/pubmed/24900885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500039g
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