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Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of FimH
[Image: see text] Antagonists of the FimH adhesin, a protein almost universally present at the extremity of type-1 fimbriae expressed by Escherichia coli, have been abundantly in the spotlight as alternative treatments of urinary tract infections. The antagonists function as bacterial antiadhesives...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027451/ https://ncbi.nlm.nih.gov/pubmed/24900609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400269v |
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