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Design and Synthesis of Peptide YY Analogues with C-terminal Backbone Amide-to-Ester Modifications
[Image: see text] Peptide YY (PYY) is a gut hormone that activates the G protein-coupled neuropeptide Y (NPY) receptors, and because of its appetite reducing actions, it is evaluated as an antiobesity drug candidate. The C-terminal tail of PYY is crucial for activation of the NPY receptors. Here, we...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027376/ https://ncbi.nlm.nih.gov/pubmed/24900634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400335g |
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