The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

Post-translational modifications (such as ubiquitination) of clock proteins are critical in maintaining the precision and robustness of the evolutionarily conserved circadian clock. Ubiquitination of the core clock transcription factor BMAL1 (brain and muscle Arnt-like 1) has recently been reported....

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Hlavní autoři: Gossan, Nicole C., Zhang, Feng, Guo, Baoqiang, Jin, Ding, Yoshitane, Hikari, Yao, Aiyu, Glossop, Nick, Zhang, Yong Q., Fukada, Yoshitaka, Meng, Qing-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027211/
https://ncbi.nlm.nih.gov/pubmed/24728990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku225
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