טוען...
Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides
Antisense oligonucleotides (ASOs) are synthetic oligonucleotides that alter expression of disease-associated transcripts via Watson–Crick hybridization. ASOs that function through RNase H or the RNA-induced silencing complex (RISC) result in enzymatic degradation of target RNA. ASOs designed to ster...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027159/ https://ncbi.nlm.nih.gov/pubmed/24589581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku184 |
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