PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways

The repair of toxic double-strand breaks (DSB) is critical for the maintenance of genome integrity. The major mechanisms that cope with DSB are: homologous recombination (HR) and classical or alternative nonhomologous end joining (C-NHEJ versus A-EJ). Because these pathways compete for the repair of...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Beck, Carole, Boehler, Christian, Guirouilh Barbat, Josée, Bonnet, Marie-Elise, Illuzzi, Giuditta, Ronde, Philippe, Gauthier, Laurent R., Magroun, Najat, Rajendran, Anbazhagan, Lopez, Bernard S., Scully, Ralph, Boussin, François D., Schreiber, Valérie, Dantzer, Françoise
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027158/
https://ncbi.nlm.nih.gov/pubmed/24598253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku174
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares