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Using Network Biology to Bridge Pharmacokinetics and Pharmacodynamics in Oncology
If mathematical modeling is to be used effectively in cancer drug development, future models must take into account both the mechanistic details of cellular signal transduction networks and the pharmacokinetics (PK) of drugs used to inhibit their oncogenic activity. In this perspective, we present a...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026631/ https://ncbi.nlm.nih.gov/pubmed/24005988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2013.38 |
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