Protein Kinase D Isoforms Differentially Modulate Cofilin-Driven Directed Cell Migration

BACKGROUND: Protein kinase D (PKD) enzymes regulate cofilin-driven actin reorganization and directed cell migration through both p21-activated kinase 4 (PAK4) and the phosphatase slingshot 1L (SSH1L). The relative contributions of different endogenous PKD isoforms to both signaling pathways have not...

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Autores principales: Döppler, Heike, Bastea, Ligia I., Borges, Sahra, Spratley, Samantha J., Pearce, Sarah E., Storz, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026536/
https://ncbi.nlm.nih.gov/pubmed/24840177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098090
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