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Protein Kinase D Regulates Cofilin Activity through p21-activated Kinase 4
Dynamic reorganization of the actin cytoskeleton at the leading edge is required for directed cell migration. Cofilin, a small actin-binding protein with F-actin severing activities, is a key enzyme initiating such actin remodeling processes. Cofilin activity is tightly regulated by phosphorylation...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190831/ https://ncbi.nlm.nih.gov/pubmed/21832093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259424 |
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