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Protein Kinase D Regulates Cofilin Activity through p21-activated Kinase 4

Dynamic reorganization of the actin cytoskeleton at the leading edge is required for directed cell migration. Cofilin, a small actin-binding protein with F-actin severing activities, is a key enzyme initiating such actin remodeling processes. Cofilin activity is tightly regulated by phosphorylation...

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Main Authors: Spratley, Samantha J., Bastea, Ligia I., Döppler, Heike, Mizuno, Kensaku, Storz, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190831/
https://ncbi.nlm.nih.gov/pubmed/21832093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259424
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