Human Sarcoma Growth Is Sensitive to Small-Molecule Mediated AXIN Stabilization

Sarcomas are mesenchymal tumors showing high molecular heterogeneity, reflected at the histological level by the existence of more than fifty different subtypes. Genetic and epigenetic evidences link aberrant activation of the Wnt signaling to growth and progression of human sarcomas. This phenomeno...

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Main Authors: De Robertis, Alessandra, Mennillo, Federica, Rossi, Marco, Valensin, Silvia, Tunici, Patrizia, Mori, Elisa, Caradonna, Nicola, Varrone, Maurizio, Salerno, Massimiliano
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026528/
https://ncbi.nlm.nih.gov/pubmed/24842792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097847
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