Human Sarcoma Growth Is Sensitive to Small-Molecule Mediated AXIN Stabilization

Sarcomas are mesenchymal tumors showing high molecular heterogeneity, reflected at the histological level by the existence of more than fifty different subtypes. Genetic and epigenetic evidences link aberrant activation of the Wnt signaling to growth and progression of human sarcomas. This phenomeno...

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Bibliographische Detailangaben
Hauptverfasser: De Robertis, Alessandra, Mennillo, Federica, Rossi, Marco, Valensin, Silvia, Tunici, Patrizia, Mori, Elisa, Caradonna, Nicola, Varrone, Maurizio, Salerno, Massimiliano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026528/
https://ncbi.nlm.nih.gov/pubmed/24842792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097847
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